L O A D I N G

ADDITIVE MANUFACTURING AND BIOFABRICATION

2018 SUMMER SCHOOL AT ETH ZÜRICH

27 - 31 AUGUST 2018



Where:

ETH Hönggerberg
Building HIT
Room H42




Deadline Extended: 15 July 2018









3D Printing

Imagine, create, make... or buy?

Should you use additive manufacturing? What is the motivation to go for additive manufacturing? Which process suits your application? Make or buy? This introduction to the additive manufacturing of polymers will give you hints how to answer those questions.

Considering additive manufacturing as a toolbox, most common methods to construct 3D structures with polymers are introduced in this series of presentations. Specificities and limitations of each method are given. Main presented methods are SLA/DLS, powder binding, extrusion and material jetting. Experts in the field will explain what 3D printing can be used for and introduce cutting edge technology like metal 3D printing or 3D printing of functional electronics. You will have the chance to listen to leading companies and to try out 3D printing yourself during a hands-on session.

Bioprinting

The future of printing Tissues and Organs?

How does bioprinting work? How does the future of bioprinting looks like? What other applications are there for bioprinting? If you ever wondered about these questions and wanted to learn how to answer them, this summer school is the ideal place for you to start with.

The bioprinting community is growing rapidly as the technology becomes more readily available. Research groups as well as companies use bioprinting to create tissues for drug testing and to develop organs for transplantations. This part of the summer school will provide you with insight on achievements, state of the art research and predictions about the future development in the bioprinting field. Highly regarded Professors will present you their work while people from leading companies in the field will teach you about the bioprinting market and challenges of this technology. To wrap all of this up, you will have the chance to explore bioprinting yourself. We provided a hands-on session during which you have the chance to use bioprinter to print your own tissue.

Organisers

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Philipp Fisch

PhD Student in Bioprinting
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Enrico Tosoratti

PhD Student in Biofabrication
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Benjamin Kessel

PhD Student in Bioprinting
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Jens Antons

PhD Student in Biomechanical Orthopedics
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Naser Nasrollazadeh

PhD Student in Biomechanical Orthopedics
15
SPEAKERS
05
DAYS
2
WORKSHOPS

Speakers

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Prof. Dr. Marcy Zenobi-Wong


ETH Zürich
Tissue Engineering & Biofabrication Laboratory
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Prof. Dr. Pierre-Etienne Bourban


EPFL
Laboratory for Processing of Advanced Composites
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Prof. Dr. Akhilesh Gaharwar


Texas A&M University
Department of Biomedical Engineering
Department of Materials Science and Engineering
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Prof. Dr. Dirk Penner


ZHAW
Laboratory of Ceramic Materials
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Dr. Christian Leinenbach


EMPA
Alloy Design for Advanced Processing Technologies Group
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Dr. Masania Kunal


ETH Zürich
Complex Materials Group
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Dr. Maité Rielland


L'Oréal
Cellular & Tissue Engineering Platform
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Dr. Mathieu Soutrenon


HEIA Fribourg
iPrint Team
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Dr. Johannes Gumpinger


European Space Agency
Structures, Mechanisms and Materials Division
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Dr. Danick Briand


EPFL
Soft Transducers Laboratory
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Marc Thruner


regenHU Ltd
CEO
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Dr. Duong Nguyen & Isabelle Bondesson


Cellink
PhD, Senior Tissue Engineer, CELLINK & MSc, Senior Skin Tissue Engineer, CELLINK
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Carlos Carvalho


envisionTEC GmbH
Process & Material Development

“Additive manufacturing could reduce energy use by 50 percent and reduces material costs by up to 90 percent compared to traditional manufacturing.”

The first day will begin with the event registration - where you will be handed your badges for the week - and a breakfast. This is an excellent occation to mingle with your fellow colleagues!

The organisers will give the start to the Summer School by welcomming you all. A short introduction will be given on the compisition and the plan for the coming week. We will introduce the speakers and their relavite area of expertiese.

Manuel Schaffner will present various 3D printing technologies and their applications. He will talk about the potential of 3D printing and give some insight on how useful the technology is for real world applications.

This presentation is a general introduction to the additive manufacturing of polymers. First are explained the main reasons to use additive manufacturing over other production methods. Then a presentation of the most common methods, the materials they use and their limitations is given. Finally, recent developments and trends in additive manufacturing are presented.

Everyone is welcome in the area just outside the lecture hall to enjoy lunch. Different options are available.

More and more materials are used in additive manufacturing offering complex geometric parts with integrated functions. Different polymer types and grades are continuously developed to provide required properties being biocompatibility, resorbability, permeability to liquid… while keeping desired mechanical integrity under loading. At the same time, the transformations of the composition and morphology of the polymer materials during their processing dictate the final performance. The phenomena controlling the polymer transformations during fusion 3D printing technologies are presented. By exploiting them, unique combinations of soft and strong materials or direct foam printing could be proposed. Adding fillers, particles or fibres to the polymers influences the transformation phenomena but will offer even wider design freedom.

His talk will give an overview of the current state of research and industrial implementation of additive manufacturing technologies of ceramics with a focus on examples from the field of medical applications.

A short coffee break will follow to stretch your legs.

A group discussion will follow where you will all have the chance to exchange ideas and background experiance between one another.

Metal additive manufacturing (AM) techniques are powder-based, layer by layer methods which can directly build 3D structures with intricate geometries onto substrates. They offer a unique ability to dynamically mix materials during the deposition process and produce functionally graded structures, new composite microstructures and perhaps even new material classes. AM has clear advantages in small series and highly individualized products for aerospace, automotive or medical industry. This lecture will give an introduction into the different AM technologies that are used for metals with a special emphasize on biomedical applications. In addition, the challenges related to the AM of metals and the economic aspects will be briefly discussed.

A short coffee break will follow to stretch your legs.

Everyone is welcome in the area just outside the lecture hall to enjoy lunch. Different options are available.

His lecture in the frame of the summer school on 3D Printed Electronics will cover the hybrid integration of printing technologies (2D, 2.5D, and 3D) for the realisation of customized smart systems. An overview on flexible and printed electronics will be given covering materials, printing processes, components and applications. A particular attention will be paid to the manufacturing of smart flexible systems by combining silicon and printed components. Motivations and challenges for the integration of functional electronic materials and components into 3D printed structures will be addressed. Recent developments in the hybrid integration of functional materials and components will be presented and the first realizations highlighted. In summary, the lecture will provide to the attendees the status and perspectives on the digital manufacturing of smart systems towards the 3rd dimension.

Bioprinting’s great promise is to deliver tissue replacement grafts which are personalized in terms of geometry, materialproperties and the patient’s own cells. Current bioprinted constructs are fabricated from relatively inert and soft biomaterials, limiting their performance in in vivo weight-bearing applications. New generations of bioinks are needed to increase the biological and mechanical properties of printed tissues. Our laboratory focuses on the incorporation of key biological signals into the bioink and methods to achieve high fidelity printing of polymeric biomaterials. In the presentation, I will review the common approaches to design a bioink and methods of their characterization.

A short coffee break will follow to stretch your legs.

Since last 80’, a long time before 2013 European Union ban on animal testing for cosmetic products, L’Oréal has placed itself as a pioneer for reconstructed human skin. It became one of the first cosmetic companies testing its raw materials/ actives/formulations on in-house reconstructed human skin.
Bioprinting is a great alternative to create new models of skin with a complexity that cannot be achieved only by human hands. One of the biggest potential advantages of this technology is the ability to place cells or biological material where it needs to be placed, opening a few doors for tissue engineering. It will be a tool for screening and model construction in the next few years and is already pushing us to think 3D vitro models and Tissue Engineering differently.

Thermoplastic polymers, especially PLA, PLGA, PCL and their co-polymers, belong to the most widespread materials currently used in Additive Manufacturing assisted Tissue Engineering research. Besides their most well-known use in technical 3D printing technologies, like FDM, for prototyping and surgical planning, thermoplasts have been used with 3D bioprinters for Bone Regeneration as well as Cartilage Regeneration in combination with other materials to optimize their mechanical properties to the application’s requirements. Additionally, researchers have increasingly used biodegradable polymers as reinforcement of hydrogel scaffolds, a type of hybrid scaffolds, to provide both flexibility as well as mechanical strength to cell laden implants. Lastly, thermoplastic polymers remain the gold standard for controlled drug releasing applications, which can be combined with scaffold fabrication processes.
This presentation will review the use of thermoplastic materials in Additive Manufacturing assisted Tissue Engineering during the last 15 years.

A short coffee break will follow to stretch your legs.

Everyone is welcome in the area just outside the lecture hall to enjoy lunch. Different options are available.

Our cutting edge biofabrication process creates infinite possibilities in the manufacture of artificial tissues and organs. By engineering Macro & Nano architectures in a single process unit, we have opened the door to a whole new world of possibilities allowing us to mimic biological systems identical to those found in nature. regenHU is an innovative biomedical company located in Switzerland, resulting from the joint venture between Delta Robotics Ltd and the CPA Group Ltd. regenHU acts as a biosystem architect exploiting novel bio-manufacturing solutions in order to respond to the emerging challenges facing the biomedical industry. regenHU benefits from exclusive patented technologies resulting from many years of research within International Universities and partners. Advancements in medical Science, biology, cell-based therapies, as well as the ever increasing market entry barriers induced by biomedical product regulations and legislations, ask for innovative solutions to create organotypic tissue models that demonstrate optimal biological relevance. It is well known nowadays that these requirements can only be fulfilled if Science is able to mimic natural morphologic environments of cellular components. This breakthrough aspect can only be approached by the exploration of the third dimension: regenHU innovate 3D Tissue Engineering.

The key to advancing 3D bioprinting as a company is having diversity in products, technologies, and expertise. At Cellink, e were the first bioink company. That was 3 years ago. We have grown to be one of the leading companies for bioinks nd bioprinters with offices worldwide. We develop bioprinters with flexible capabilities to meet the needs of scientists in issue engineering, drug development, and biomaterials. In addition, our bioink collection can compliment research needs f clinicians, engineers, and students.

A short coffee break will follow to stretch your legs.

You will have a chance to explore and use in first persion high end quality FDM 3D printers and Bioprinters to apply what you have learned throught the week.

A short coffee break will follow to stretch your legs.

You will have a chance to explore and use in first persion high end quality FDM 3D printers and Bioprinters to apply what you have learned throught the week.

Everyone is welcome in the area just outside the lecture hall to enjoy lunch. Different options are available.

You will have a chance to explore and use in first persion high end quality FDM 3D printers and Bioprinters to apply what you have learned throught the week.

A short coffee break will follow to stretch your legs.

You will have a chance to explore and use in first persion high end quality FDM 3D printers and Bioprinters to apply what you have learned throught the week.

As the week comes to an end, you will all be invited to a dinner in one of the best restaurants in Zürich, where you will have more time to network and have some fun!

As the first day, you will be served breakfast before starting with the presentations.

During the groupwork you performed yesterday, you should have prepared a presentation in which you explain and show what you have achieved.

Everyone is welcome in the area just outside the lecture hall to enjoy lunch. Different options are available.

The summer school will end with the nomination of the presentation winners and with a short closing ceremony.

After all the hard work, it is time to start the weekend off with a BBQ at the Zürich Lake. When the Closing Ceremony is over, we will start moving to the Lake of Zürich to go swimming, have some fun, relax and have a BBQ in the evning. Those who will still be in Zürich are welcome to join.

DOWNLOAD THE SCHEDULE

Friday afternoon: Lake Zürich






“A New Era for 3D Bioprinting Breakthroughs - How 3D Bioprinting Could Revolutionize Organ Replacement”

Prices

Apply for one of the 30 spaces and get access to
  • Open breakfast, lunch, dinner
  • Talks from world renowned scientists
  • Talks from world leading companies
  • Hands on - two workshops
  • Industry day - chat with world leading AMF companies
Master students
CHF 100
APPLY NOW (9 places)


Doctoral students
CHF 250
APPLY NOW (21 places)



Postdocs also welcome!


DEADLINE: 15 JULY 2018

Sponsors

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...
...
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Otto-Stern-Weg 7, 8093 Zürich

ambss@ethz.ch

+41 44 633 09 29

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